Sildenafil is used to treat pulmonary arterial hypertension and to improve penile functions.
Sildenafil: Phosphodiesterase type 5 (PDE 5) inhibitors
Sildenafil works by blocking the effects of certain enzymes (PDE5) within the body which limits blood flow to the lungs and penis. As a result, it causes widening of blood vessels (arteries) supplying these organs, increases blood flow and oxygen supply and improves their functions.
Consult your doctor if you experience:
Take this medicine in conjunction with a multivitamin that contains zinc, riboflavin, nitric oxide and progesterone. Before taking this medicine, inform your doctor about the quantity of fat you are carrying, including grapefruit, grapefruit juice,* tablet, capsule and grapefruit juice, diabetes, high blood pressure and heart and kidney disease. You should also do not consume grapefruit juice while taking this medicine as it may interact with it.
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What is Erectile Dysfunction? This condition, also known as erectile dysfunction, is a common condition that affects men of all ages. If left untreated, it can lead to trouble every time. The symptoms of Erectile Dysfunction can include:Erectile Dysfunction can have several causes. With the rising prevalence of these common issues, it's no wonder that there is a demand for understanding the causes of these dysfunctions.
One of the most common causes of dysfunctions is where sexual desire or desire cannot be regulated. This can result in disappointment with future sexual encounters. Medications like Erectile Dysfunction belong under the category of Phosphodiesterase type 5 (PDE5) inhibitors. They work by blocking the phosphodiesterase enzyme that breaks down cyclic guanosine monophosphate (cGMP) into phosphates, which are essential for maintaining the health of blood vessels and the penis.
While cGMP is essential for maintaining the health of the blood vessels, PDE5 inhibitors manage PDE5 molecules by directly hydrolyzing monophosphate (i.e. diphosphate) to phosphates, which are needed for cGMP breakdown. This action allows cGMP molecules to flow more easily through the smooth vascular tissue of the penis while causing increased blood flow in the target area. As a result, increased blood flow is felt in the initial stages of sexual activity.
Since PDE5 inhibitors' action leads to increased levels of dilation of the blood vessels, they are known as PDE5-inhibitors. These medications inhibit the action of PDE5 enzymes, which can allow more blood to flow into the penis and facilitate an erection. Phosphodiesterase-5 inhibitors are commonly prescribed for erectile dysfunction, and they offer advantages over PDE5 inhibitors for sexual dysfunction.
This article looks at how long it takes for a medication to start working for certain individuals and whether it's best to have a doctor or chemist to prescribe it for you. It's also covers the risks of taking it for too long and if you decide that it's the right treatment for you, it's important to talk to your healthcare provider before you take it. We'll get to more about each individual, and how to best use your time on these medications, which might be more convenient for you.
How long do the effects of sildenafil last?
It has an onset window of 2-6 hours for sildenafil to start working, and you should see a noticeable difference between when it's taken and after. Typically, it stays in your system for a few hours and then goes off-loaded. The drug will then work its magic on those who take it, and those who take it for a long period of time.
Do I need to take it daily?
It's important to know if you have any ongoing conditions or are taking any other medications. It's also important to be aware of any side effects that might occur if you take it. Common side effects include headaches and dizziness, and if they do not get better or get better, or if they get worse, you should speak to your doctor.
What should I tell my doctor before I take this medication?
Before you take sildenafil it's best to tell your doctor about any health conditions you have, and any medications you are currently taking. They can help you understand the risks and benefits of taking this medication and how to use it safely.
If you have any concerns about taking this medication, talk to your doctor or pharmacist.
They may also send a message to your healthcare provider.
What are the possible side effects of sildenafil?
Like all medications, sildenafil can have side effects. Common ones include headaches, facial flushing, and nasal congestion. More serious side effects can occur and require medical attention.
Some of the most common side effects of sildenafil include the following:
It's important to tell your doctor about all other medications you are currently taking to avoid potential side effects.
Can I take sildenafil if I have my penis in my body?
It's best to avoid alcohol and marijuana while on this medication, as they can decrease the effectiveness of the drug. However, it's also important to be honest with your doctor about any medications or supplements you are currently taking.
How do I take sildenafil?
It's best to take sildenafil about an hour before sexual activity, but you should also take your blood pressure at least twice a day, and you should avoid heavy or high-fat meals before taking the drug.
If you still have headache or dizziness after taking sildenafil, don't panic and talk to your doctor. They will probably try to adjust your dosage or suggest a different treatment. Just be sure to take the drug at least 30 minutes after having sex.
What should I watch for while on this medication?
Like all medications, sildenafil can cause unwanted side effects. Common side effects include headaches and facial flushing, and if they get worse, you should speak to your doctor.
Can I use sildenafil in pregnancy?
It's important to discuss the risks and benefits of using sildenafil during pregnancy with your healthcare provider.
Will I have to take it during breastfeeding?
It's best to breastfeed while on this medication, as it can decrease the effectiveness of the drug. Just be sure to take the drug at least 24 hours after having sex.
Will I have to take sildenafil during my surgery?
Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.
Sildenafil is available in 25mg, 50mg, and 100mg strengths.
Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.
Common side effects include:
Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.
Sildenafil should not be used by those:
Inform your doctor of all medications and supplements before use. Interactions may occur with:
Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.
Sildenafil is available by prescription only in the UK.
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